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393 Studies indicate that a lack of SIRT6 leads to reduced mitochondrial gene expression, increased production of ROS, and accelerated mitochondrial decay, collectively triggering mitochondrial dysfunction

The lack of correlation between the mRNA levels of sepp1a and sepp1b in ZF in response to Se status in the two studies suggests divergence in these genes in terms of regulation

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Biswas P., Dellanoce C., Vezzoli A., Mrakic-Sposta S., Malnati M., Beretta A., Accinni R

On the other hand, after HR development antioxidant activities and levels of GSH, increased significantly (Fodor et al., 1997)