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Key safety principles include strict sterile technique to prevent contamination and infection, proper injection site preparation and rotation, correct needle insertion angle and depth for chosen administration route (IM or SC), slow administration to minimize discomfort, and appropriate post-injection site care and monitoring

Dosing and administration of tirzepatide with B6 The tirzepatide component of the compound follows the same dose escalation protocol as standard tirzepatide

doi: 10.3390/ijtm2030036

Some of this risk can be mitigated by screening for latent TB, by immunizations against other pathogens and by cancer prevention and screening strategies such as sun avoidance and cervical cytology testing