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These adverse reactions occurred more commonly with ZEPBOUND than with placebo and occurred in at least 2% of patients treated with ZEPBOUND

[81] This complex is much more lipophilic than the water-soluble vitamin B 12 , so is able to pass through cellular membranes with greater ease

Appetite changes are less consistently reported with AOD-9604 than with semaglutide and in controlled studies, most short-term safety signals mirrored placebo rates