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Herein, we demonstrate that ACE2-expressing human lung spheroid cells (LSC)-derived exosomes (LSC-Exo) could function as a prophylactic agent to bind and neutralize SARS-CoV-2, protecting the host against SARS-CoV-2 infection

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Since there was no effect of the specific concentrations of any M-CFS, we chose 5% of the supernatants as a medium non-lethal concentration for the further part of the study