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In September 1977, the Annals of Internal Medicine published articles about patients who suffered liver damage after taking acetaminophen for an extended period of time at or slightly above therapeutic doses, underscoring what the Lancet had said about the drugs narrow margin for error

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Through application of basic pharmacokinetic principles, alongside the currently available research, we aim to demonstrate why we have found microdosing to be the most effective way of achieving hormonal balance, without fluctuations

[31] [32] In recent years, government regulatory bodies and non-profit NGOs have been set up with the declared aim of monitoring kava quality