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9 Summary The available literature indicates that non-medical use of exogenous testosterone and other anabolicandrogenic steroids (AAS) is associated with a broad spectrum of multisystem adverse effects mediated by oxidative stress, mitochondrial dysfunction, endocrine disruption, and epigenetic mechanisms

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Unlike single-agent pharmacological therapies, whole foods provide complex mixtures of micronutrients, antioxidants, polyphenols, and bioactive phytochemicals that act on multiple physiological targets (3234)