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10.1016/j.freeradbiomed.2015.03.014 Free Radic

doi: 10.1167/iovs.19-28250

In terms of sensitivity, crystallographic screening cannot be compared to any other technique, being able to identify ligands with affinities as low as sub-nanomolar and having the compound's solubility as a limit 89

The SCN1A gene belongs to a family of genes that provide instructions for making sodium channels that transport positively charged sodium ions into cells, play a key role in a cell's ability to generate and transmit electrical signals