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Furthermore, the findings of a preclinical study examining the efficacy of recombinant human IL-7 (rhIL-7) as a lymphostimulating intervention in sepsis revealed that the ex vivo administration of rhIL-7 to patients cells resulted in a noteworthy enhancement of lymphocyte functionality in various aspects, including the proliferation of CD4(+) and CD8(+) lymphocytes, the production of IFN-, the phosphorylation of STAT5, and the induction of B cell lymphoma 2 following stimulation (Venet et al., 2012)

Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors

CY: Supervision, Validation, Writing review & editing

J Proteomics (2014) 101:13040