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These include physical disruption, nanocarrier systems, and direct nose-to-brain delivery, with each expanding therapeutic access to the central nervous system (CNS) while maintaining safety and translational feasibility

I., Veltman, D

CJC-1295 with DAC (Drug Affinity Complex) has an extended half-life of about 6-8 days, providing sustained GHRH receptor activation but potentially disrupting natural GH pulsatility