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A recent meta-analysis has shown that smoking is associated with poorer treatment outcomes, delayed conversion to negative smear or culture, and higher dropout rates from treatment plans, ultimately leading to a lower likelihood of treatment success (E

Furthermore, curcumin administration significantly attenuates mitochondrial swelling, reduces lipid peroxidation and protein carbonyl formation, and decreases ROS production in HD rats ( 5 Strategies to enhance the bioavailability and pharmacological efficacy of curcumin 5.1 Poor bioavailability of curcumin Although curcumin has demonstrated excellent pharmacological activities, the extremely low bioavailability significantly restricts its clinical application in disease prevention and treatment