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Causes of Interstitial Cystitis The exact cause of IC is unknown

Caruso P, Dunmore BJ, Schlosser K, Schoors S, Dos Santos C, Perez-Iratxeta C, et al

Similar to CD4 + T cells, in which LDHA is induced by TCR stimulation [108], antigen-specific CD8 + T cells also upregulate the expression of LDHA upon activation [181]