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274 Prion diseases are caused by accumulation of a pathological prion, known as Prion PrP Sc , which are misfolded polypepetides converted form physiologically significant cell-surface glycoprotein PrP C encoded by the PRNP gene

Multiple catalytic effects of nanozymes Nanozymes, characterised by their biomimetic catalytic activity, high stability, and programmable nature, offer a novel strategy to address the limitations of traditional enzyme preparations [135]

Sphingosine kinase (SPHK) is a rate-limiting enzyme involved in the synthesis of S1P and plays a pivotal role in maintaining the integrity of the intestinal epithelial barrier (Li et al., 2023d)

Under physiological conditions, hepatocytes are resistant to TNF-induced hepatotoxicity