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Before the ruthenium complex can be used clinically, numerous problems need to be addressed, including strategies to improve the hydrolysis of ruthenium complexes to achieve effective absorption and better metabolism, as well as enhance their cellular penetration to achieve targeted tumor cell death

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Unique to the clinical diagnosis of T1D is the detection of autoimmune markers for autoantibodies to insulin, glutamic acid decarboxylase (GADA), islet antigen 2, or zinc transporter 8 in addition to elevated blood glucose levels (46)