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doi: 10.1038/sj.tpj.6500369 135 LuCHYangCYLiCYHsiehCYOuHT

Retrospective analysis of data generated during therapeutic trials has indeed offered elements supportive for responses to therapeutic agents depending on the intrinsic subset of the treated individual

Furthermore, several studies using 13 C 5 -glucose tracer analysis have shown that HIF1 activation but also HIF2 activation leads to reduced glucose-dependent 13 C 5 -citrate generation (Wise et al., 2011