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Description

Inside the cells lactate remains in equilibrium with pyruvate due to very high activity of lactic dehydrogenase

Chalam, K

These changes are expected to reduce administrative burden, ensure compliance with existing MDPP regulations, and streamline data reporting for MDPP suppliers

As this enzyme catalyzes a reversible reaction between isocitrate and -ketoglutarate, the inverse reaction, so called the reductive carboxylation, could occur to maintain TCA cycle intermediates under mitochondria defects