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doi: 10.1186/s40364-022-00433-w 98 YangW

(6) For metabolic patients, this matters considerably

Failure to clear ACs leads to their secondary necrosis, triggering inflammation, disruption of self-tolerance, and immune activationa major contributor to SLE pathogenesis (318321)

Lipid regulation of OL responses As OLs extend up to 60 myelinated processes and can generate up to 50 10 3 m 3 of membrane per day, myelination and remyelination are highly demanding processes