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Patients with Mitochondrial Disease: There is an increased risk of valproate-induced acute liver failure and resultant deaths in patients with hereditary neurometabolic syndromes caused by DNA mutations of the mitochondrial DNA Polymerase (POLG) gene (e.g

Djearamane, S., Xiu, L.-J., Wong, L.-S., Rajamani, R., Bharathi, D., Kayarohanam, S., Selvaraj, S

The reduction in MDA levels, observed particularly in the D4 group, suggests that nano-liposomal VC effectively scavenges reactive oxygen species (ROS), reducing cellular oxidative damage

Oxidative stress as a potential mechanism underlying membrane hyperexcitability in neurodegenerative diseases