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BBB blood- brain barrier most approaches to delivery have utilized gene therapy methods with the hope that the growth factor will be expressed in the correct location at a high enough concentration and for a long enough period to provide clinical relief

Individual Response: Peptides can have variable effects from person to person

More impressively, in the chronic unpredictable stress model (a more severe, clinically relevant paradigm), BPC-157 maintained effectiveness at both 4-day and 6-day assessments while imipramine 30 mg daily only became effective after prolonged treatment

The compound has been studied in detail and promising pharmacological data have been reported