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Due to the prevalence of hypertension, diabetes, obesity and other diseases that cause kidney damage, the incidence of chronic kidney disease (CKD) is also on the rise year by year and has been one of the most serious illnesses that jeopardize human health (1)

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Finally, the analysis of the predicted metabolites revealed that AcM could enhance the production of microbial molecules related to lipid-metabolism, active metabolites and neurotransmitters (valeric/isovaleric acid, azelate, azelaic acid, anandamide C20:4, carnitine and undecanedioic acid), metabolism of vitamins and nucleotides/nucleosides, whilst possibly depleting inosine