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While supplementing with up to 2,000 mcg of B12 is considered safe for treating deficiencies, it is advisable to consult a healthcare professional to determine if supplementation is necessary, especially if you are taking medications or are pregnant

2008 Sep;16(9):2081-7

Oral B12 Traditionally, vitamin B12 replacement has been administered orally

These can include: Pain or discomfort at the site of injection Redness or swelling Itching or rash These reactions are usually mild and go away by themselves