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Acts as an antioxidant to fight oxidative stress in cells

These changes occurred before the increase in THDA levels, indicating that the loss of BDNF-TrkB signalling and upregulation of GSTO2 happens before the hyperdopaminergic state, as with the Trkb Penk -KO mice, supporting that GSTO2 increase is more likely a cause of neurodegeneration than a consequence of it

If the ferrous heme (Fe 2+ ) iron contained in the prosthetic group of Hb is oxidized to ferric (Fe 3+ ) heme to form methemoglobin (metHb), the affinity of the protein toward oxygen is dramatically decreased

The result is presented as a report field only