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Recalls & Warnings March 25, 2002 FDA Advises Consumers of Risk of Severe Liver Toxicity with Kava On March 25, 2002 the U.S

Karin, "ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development", Cancer cell , 2014 , 26 (3), 331

These results highlight the mechanisms by which G6PD dysregulation may contribute to cancer or autoimmune diseases

Overdose results in serotonin syndrome, a condition where excess serotonin in the brain causes agitation, confusion, muscle rigidity, and in extreme cases, coma