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Description

Third-generation EGFR-TKI osimertinib, developed to overcome T790M mutation-driven resistance, is now a first-line option for advanced EGFR-mutant NSCLC [3, 4]

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Platelet MAPK signaling molecules mainly include ERKs (extracellular-signal-regulated kinases), JNKs (Jun amino-terminal kinases), and p38/SAPKs (stress-activated protein kinases)

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7.1.4 Response to treatment should be assessed after exclusion of sub-optimal dosing, non-adherence, alternative etiologies, co-morbidities, and autoimmune sclerosing cholangitis/overlap syndrome (LOE 5, Strong recommendation)

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Jordan J Bio Sci 4:119124 Malgorzata Nita, Andrzej Grzybowski (2016) The role of the reactive oxygen species and oxidative stress in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults

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