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2025 Oct 25

Thus, substantial and mounting evidence supports a direct contributory role of gut microbiota as a participant in CVD pathogenesis, and preclinical studies indicate that the therapeutic targeting of microbial contributors to the TMAO metaorganismal pathway may hold promise as a novel approach for the prevention or treatment of CVD

Exclusion criteria were considered exacerbated COPD patients requiring systemic corticosteroids and/or antibiotic therapy, positive skin tests for common aeroallergen extracts and history of asthma and/or allergic rhinitis