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As SLEs immune dysregulation is so complex and with the very real possibility of herb-drug and supplement-drug interactions, PK/PD studies are imperative (233)

The presence of benzyl alcohol extends the usability of BWFI, but this extension is not indefinite and requires careful management

The decrease in cell viability was almost completely rescued by either iron chelation via deferoxamine (DFO) or by the lipophilic antioxidant ferrostatin- 1 (Fer1), demonstrating that cell death is both iron and reactive- oxygen species (ROS) dependent