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Eur J Pharm Sci (2020) 152:105450

The most affected autoimmune conditions during menopause include: Hashimotos thyroiditis (more fatigue, hair loss, weight gain) Rheumatoid arthritis (increased joint pain and stiffness) Lupus (more frequent or severe flares) Multiple sclerosis (increased fatigue and cognitive issues) Endometriosis (can still flare despite estrogen decline) Can hormone replacement therapy (HRT) help autoimmune symptoms