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Copper promotes conversion of dopamine into norepinephrine, increasing anxiety, irritability, and sensory sensitivity

Many point sources of pollution, such as mining, textile industries, chemicals manufacturing and formulating facilities, food processing, and pharmaceutical production discharge waste containing water into lotic ecosystems in Sri Lanka

Since inflammation of the large intestine affects brain function through braingut interaction, patients with colitis are at a high risk of developing psychiatric disorders, such as depression and anxiety, during the exacerbation period 43,44