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The fact that HSV-1 is not invisible to the immune system and that immune cells are commonly found adjacent to infected cells, suggests scenarios in which immune cells infiltrating the CNS may somewhat contribute to chronic inflammatory processes that can be detrimental to the function of this tissue (White et al., 2012

Although VEGF is not an inflammatory cytokine, VEGF can induce the activation of the transcription factor NFAT in endothelial cells via PLC/calcineurin, promoting an inflammatory gene expression pattern similar to that of IL-1 [129]

Here, "reduced" refers to a reducing agent, which stands in opposition to an oxidizing agent

Cathepsin C inhibitors: property optimization and identification of a clinical candidate