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For instance, the brain energy consumption accounts for over 20% of the total in order to coordinate with neural activities [6,7,8] and the skeletal muscles can quickly activate metabolic pathways for ATP synthesis during exercise [9]

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h , Bar graph showing relative fold change (log 2 ) in top 27 ER proteins of IP samples from ER-tag cells compared to those from control-tag HEK293T cells or to whole-cell lysate from ER-tag HEK293T cells