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While glutamate receptor activities tune the developing GABAergic synapse [2], GABA is now considered the main excitatory transmitter during early development, acting not only at a synaptic and network level, but also on cell cycle and migration [1]

This process leads to the release of cellular cytokines known as damage-associated molecular patterns (DAMPs), which promote a proinflammatory state (Yuan et al., 2024)

For instance, the addition of monovalent cations, such as NH 4 + to a final 0.1 M peptide (poly (Glu-Leu)) solution, induces a transition to a water soluable beta-structure

Week one, inject in the left abdomen