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Description

The findings highlighted that alterations in specific positions within the peptide structure could markedly reduce receptor affinity and intrinsic activity, indicating how structural changes in GRF analogues could impact their receptor interactions and consequent side effects

Mol Endocrinol 25:16001611

Blood 2007 Dec 1;110(12):4111-9

Ipamorelin is a selective GHRP (Growth Hormone Releasing Peptide) that also boosts growth hormone levels but does so with minimal impact on cortisol or prolactin, reducing the risk of side effects