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Holzer H, Duntze W: Metabolic regulation by chemical modification of enzymes

Multiple evidences show that alterations in various metabolic circuits directly contribute to the tumorigenic process at different levels (e.g

Thus, it depends on the nature and the severity of the disorder, condition or disease to be treated, and also on the sex, age, weight and individual responsiveness of the human or animal to be treated, on the efficacy and duration of action of the compounds used, on whether the therapy is acute or chronic or prophylactic, or on whether other active compounds are administered in addition to compounds of Formula I