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The FDA's 2023 PCAC briefing document cited insufficient clinical evidence to support therapeutic compounding approval

doi:10.1016/j.dld.2019.09.016 2024 The Author(s)

Seek urgent medical help (call NHS 111 or 999) if you develop severe persistent abdominal pain (which may indicate pancreatitis) or signs of a serious allergic reaction such as difficulty breathing, severe rash, or swelling of the face, lips or throat

A recent study has examined the effect of cobalamin supplementation on the outcomes of treatment for feline patients with severe cobalamin deficiency and histories suggesting chronic gastrointestinal disease.5 In this study, serum concentrations of methylmalonic acid normalized following parenteral cobalamin supplementation, indicating that cobalamin deficiency was the cause of the high methylmalonic acid in serum