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The top dose produced 20.9% average weight loss over 72 weeks and 20.2% in a direct comparison with semaglutides 13.7%. Its second receptor, GIP, separates tirzepatide from approved single-receptor GLP-1 drugs and helps explain the larger population-level weight loss. That 20.9% came from participants averaging about 105 kg at a BMI of 38, most of whom were sedentary

If you are experiencing these symptoms, check with your physician as soon as you can

Common symptoms include: Hematologic : Macrocytic (megaloblastic) anemia Pallor and shortness of breath on exertion Neurological : Paresthesias (tingling, pins and needles) in hands and feet Gait disturbances and balance problems Cognitive changes: memory lapses, brain fog, mood swings Gastrointestinal : Glossitis (inflamed tongue) Appetite loss and weight changes Nausea or diarrhea Because the nervous system can be permanently damaged if deficiency persists, early detection and correction are paramount