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Given the high genetic and phenotypic relevance of the available mouse models of 22q11.2DS, they provide, potentially, a unique opportunity to corroborate newly identified phenotypes in patients and to study the pathogenetic mechanisms underlying the brain-related deficits

Based on its conversion according to body surface area and detection sensitivity, 100 g/300 Ci/kg [3H]BPC157 was used for tritium labeling experiment in rats, 20, 100, and 500 g/kg of BPC157 was used for unlabeled experiment in rats, and 6, 30, and 150 g/kg of BPC157 was used for unlabeled experiment in dogs

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