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Description

Rapid urbanization is intensifying this trend, as city dwellers actively seek nutritional interventions to combat oxidative stress, environmental pollution exposure, and immune system challenges

Notably, CYP79F1 shows partial functional redundancy with its paralog CYP79F2, which specializes in longer-chain (5C-6C) substrates, providing metabolic flexibility in glucosinolate profiles (28)

J Biol Chem 278, 4096740972 (2003)

First-generation activators, including natural isothiocyanates like sulforaphane (SFN) and fumaric acid esters like dimethyl fumarate (DMF), demonstrated in vitro efficacy but failed to reach advanced clinical translation