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Melanotic hyperpigmentation Download Scientific Diagram Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Pigmented macule on the mandibular gingiva (a, case 1), affecting the Download Scientific Diagram Oral Mucosal Melanosis IntechOpen
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