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Description

GLP-1 receptors occur at high density in the heart

In islet cells, increased intracellular ATP/ADP ratio leads to closure of KATP channels and an influx of calcium ions, resulting in insulin secretion

Int J Biol Macromol 136:2026

The limitation of glucose and amino acids within the TME can significantly affect the T cell response and the determinants of metabolic dysfunction and associated T cell exhaustion within the TME are also being explored