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The change in t was of a similar magnitude to the change in CL: approximately 1.5fold for participants with mild renal impairment, approximately 1.8-fold for participants with moderate renal impairment, and approximately 4.0-fold for participants with severe renal impairment compared with their respective normal-to-match groups

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This is what the different esters look like, over a six month period: Figure 4 Approximate daily release of Testosterone at 250mg of Sustanon every 3 weeks with each ester highlighted in the legend Combining the esters to achieve an average will give this: Figure 5 Approximate average daily release of Testosterone using Sustanon at 250mg every 3 weeks The peaks and troughs are clearly significant, and it would take considerable time for the decanoate ester to achieve stable levels