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The ICE-CBF-COR pathway in cold acclimation and AFPs in plants

Furthermore, research indicates that CPS1, the key enzyme in the urea cycle, is predominantly expressed in hepatocytes and certain renal cells, with low or absent expression in most immune cells due to the urea cycles inactivity in these cells (134, 135)

Tryptophan deprivation results in diminished proteosynthesis and decreased activation of the rapamycin pathway, perhaps contributing to polyneuromyopathy [71]