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Description

BPC-157 was first synthesized from gastric fluid in the stomach

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It is acylated at the N-terminus with a C20 fatty diacid linked via a -glutamic acid spacer, and carries an intramolecular disulfide bond between Cys3 and Cys8 structural modifications that extend its half-life and reduce fibril formation relative to native amylin

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Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, et al

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Inhibition of cellular autophagy in proximal tubular cells of the kidney in streptozotocin-diabetic and uninephrectomized rats

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