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doi:10.1016/j.pneurobio.2014.11.004 Evidence-Base Disclosure The published evidence base for Dihexa consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments

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The protein expression levels of tight junction associated protein-1 (ZO-1), Occludin, inflammatory factors interleukin (IL)-6, IL-1 and tumor necrosis factor (TNF)-, SIRT1, STAT3, p-STAT3, and retinoic acid receptor-related orphan receptor gamma t (RORt) were detected by Western blot

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