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Our group investigated the efficacy of the PARPi rucaparib analogue that was conjugated to IR-786

The intracellular glutathione content of the GCI/ SER2 (2.8 0.8%), GCI/ SER1 (2.3 0.2%), GCI/ SER3 (3.2 0.2%) , GCI/ SER33 (2.9 0.1%), GCI/ SER3 / SER33 (2.5 0.2%), and GCI/ SERs (2.5 0.2%) at 48 h were higher than that of the vector control GCI strain (1.6 0.1%) (Fig