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doi: 10.1016/j.mib.2018.10.004 24 KutluM.SusuzF

AOD-9604 operates independently of GH receptors and doesn't engage the broader GH signaling cascade that produces IGF-1 elevation

As such it plays a major role in the pathology of AD where it is crucially involved (with co-chaperones such as the immunophilins FKBP51 and FKBP52) in the control of aberrant phosphorylated tau protein [67]

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