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For patients already on hormone replacement therapy (HRT), the notion of reducing senescent cell load may complement hormone optimisation by reducing the age burden on the tissues

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10.1186/1477-3155-10-16 207 XuM.HalimuG.ZhangQ.SongY.FuX.LiY.et al (2019)

BMDL and BMDU of the 95%CI of BMD with a 10% reduction in eGFR were based on (A) exponential, (B) Hill, (C) natural logarithmic and (D) inverse exponential dose-response models