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Maintaining the skin barrier through appropriate moisturization reduces the triggers that initiate inflammatory cascades

The potential activation of the GHRH receptor by Tesamorelin & Mod GRF and the potential cAMP-PKA signaling cascade may stimulate hGH synthesis and secretion from somatotrophs in the pituitary gland

[36,37] It has also been shown to exhibit senomorphic effect, attenuating SASP factors including IL-6, IL-1and C-X-C motif chemokine ligand 1 gene (CXCL-1), predominantly via inhibition of NF-B pathway