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doi: 10.1097/MPG.0000000000001422 31 Felgus-LavefveL.HowardL.AdamsS

Chen BL, Chen YQ, Ma BH, Yu SF, Li LY, Zeng QX, Zhou YT, Wu YF, Liu WL, Wan JB, et al

B) Under conditions of APAP overdose along with iron overload, excessive cellular free iron reacts with mitochondrial reactive oxygen species (ROS) to induce lipid peroxidation (LPO) of membranes