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Neuroprotective: Provides antioxidant protection to help reduce oxidative stress on neurons

2025 May 12;43(5):937-954.e9

If, during the cardiovascular evaluation, the patient's medical history or electrocardiographic investigations reveal findings indicative of or consistent with coronary artery vasospasm or myocardial ischemia, dihydroergotamine mesylate nasal spray should not be administered (see CONTRAINDICATIONS)