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This improvement was accompanied by an increase in DAT binding on DaTscan imaging, suggesting a potential neuroprotective effect and enhancement of dopaminergic function

The single human musculoskeletal paper that gets cited often is a small retrospective case series of intra-articular BPC-157 injections for multiple types of knee pain. It reported improvement in 11 of 12 patients, but the study has major limitations: no control group, no standardized objective outcome measures, no imaging confirmation of pathology, and unclear diagnostic specificity

However, some biotransformation products have enhanced activity or toxic properties

In another study, CSA-13 and CSA-131 effectively reduced the inflammatory response associated with Gardnerella vaginalis infection