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Although the effects of sirtuins on CVDs are well-established, the current understanding of their systemic and common mechanisms remains limited [54]

Figure 6 It is crucial to highlight that inorganic nanomaterials, especially those relying excessively on ROS-based mechanisms, may have limited effectiveness against aerobic bacteria highly resistant to ROS ( 2 ), and modifying nanoparticle surfaces with chitosan (Cs) and PEG to produce positively charged, hydrophilic organic-inorganic composite NPs ( Figure 6F )

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